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What are Hormone Pellet Insertions?

When it comes to bio-identical hormone replacement therapy (BHRT) pellets, Renū Progressive Medicine has recently joined with the BioTE® method of pellet therapy. Using the subcutaneous pellet approach to BHRT to replace the hormones men and women lose as they age, some patients report feeling symptom relief in as little as four weeks, but complete symptom relief may take up to six months. Certified BioTE providers customize each dose of pellet therapy to the patient’s needs and third-party testing maintains strict quality standards of sterility and potency to maximize safety and dosing accuracy.

Dr. Samantha Du Moulin and Dr. Nathan Wagner are now certified as BioTE Providers at Renū Progressive Medicine!

BioTE method of pellet therapy has helped thousands of people feel their best and achieve hormonal balance. Renū practitioners use BioTE method and bio-identical hormone pellets which contain bio-identical testosterone or estrogen. The pellets are placed subcutaneously in the body and release a continuous stream of bio-identical hormones. The pellets gradually dissolve and are absorbed into circulation. Collectively, BioTE practitioners have performed over 2 million pellet insertions since developing their proprietary method. Your practitioner at Renū is BioTE certified to customize each dose based on extensive lab work and standardized dosing methods.

Bio-Identical Hormone Replacement With Estrogen:

Mood swings, hot flashes, weight gain, memory and focus issues, or irregular or absent periods, are indications that estrogen levels have dropped in a woman.At Renū Progressive Medicine your practitioner can offer bio-identical hormone replacement therapy (BHRT) using estrogen (estradiol) pellets that may relieve these symptoms.
When a female patient decides to start the BioTE method, they typically require 3-4 subcutaneous pellet insertions per year to maintain consistent levels of circulating hormone within the therapeutic range. 
Bio-Identical Hormone Replacement With Testosterone:

Bio-identical testosterone pellet therapy has helped thousands of men and women feel better. Yes, though stereotypically thought of as a male hormone, testosterone is an essential hormone of female physiology.  Dealing with the symptoms of low testosterone, such as fatigue, muscle weakness, reduced sex drive, night sweats, or weight gain (especially in the belly area), can significantly affect your quality of life. Bio-identical testosterone pellets may be able to restore hormonal balance for potential candidates.

What Are the Signs and Symptoms of Low Testosterone And Hormonal Imbalance in Men?

low level of testosterone in a man means more than just a low sex drive. Hormones are important for regulating most major bodily processes. Symptoms consistent with low testosterone and other causes of hormonal imbalance include:

  • Low sex drive
  • Fatigue
  • Loss of muscle mass
  • Weight gain (especially in the waist area)
  • Decreased bone mass
  • Decreased exercise tolerance
  • Decreased motivation and drive
  • Depression and mood changes
  • Stress and anxiety  
  • Irritability
  • Brain fog
  • Elevated blood sugar
  • High cholesterol

What Are the Signs And Symptoms of Low Testosterone and Estrogen Hormones in Women?

Hormonal imbalances occur when there is too much or too little of a hormone in the bloodstream. Because of their essential role in the body, even the smallest hormonal imbalance can cause side effects throughout the body. There are a variety of symptoms of hormone imbalance in women including:

  • Fatigue
  • Night sweats
  • Hot flashes or flushes
  • Decreased sex drive
  • Weight gain
  • Trouble sleeping
  • Irritability
  • Anxiety
  • Mood swings
  • Low mood
  • Discomfort during intercourse/vaginal dryness
  • Memory and focus issues
  • Decreased bone mass and osteoporosis risk
  • Increased cholesterol and blood sugar levels
  • Thin skin issues and loss of hair
  • Decreased motivation
  • Decreased exercise tolerance and loss of muscle mass

How do I get started!

The first step to BHRT pellet insertion is consulting with our BioTE certified providers. Dr. Nathan Wagner and Dr. Samantha Du Moulin are the certified providers here at Renū. Our certified providers determine if patients are eligible for BHRT after an in-office appointment that includes a full explanation of everything involved and extensive lab work. If the patient is a candidate for BHRT using pellets, they are ready for a pellet insertion.


Insurance Coverage:

Does my insurance cover these? Well, no, unfortunately, the bio-identical pellet insertions are not covered by insurance. Your appointments and labs may be covered depending on your insurance. We are working closely with LabCorp and offering discounted labs for cash-paying patients.
What is the cost and how often do I need to come in?
The dosing schedule depends on what pellets you are having inserted and how your body metabolizes the pellets. Females generally need to have the pellets inserted 3-4 times a year while men generally need to have the pellets inserted 2-3 times per year.  Please inquire about our current prices

The Pellet Insertion Method

During an in-office visit for the pellet insertion, a patient is brought into the exam room. It is a sterile procedure that involves the following:

  • Insertion site: usually somewhere around the upper buttocks. The insertion site is determined through a physical exam.
  • The insertion site is numbed.
  • A small incision is made.
  • The hormone pellet(s) are inserted.
  • The insertion site is covered with a steri-strips and a bandage. The steri-strips and bandage can be removed in 3-7 days depending on gender.
  • The pellet dissolves over time, and the body absorbs the contents, leaving nothing behind.

Every patient’s symptoms are unique, so each journey is customized to fit your needs. Some patients report seeing improvement in as little as four weeks, but full optimization can take up to six months. Pellets do need to be re-inserted every 3-6 months depending on gender and metabolism. Labs are completed to ensure optimal dosing is reached.


Please read more about our certified BioTE Providers!

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