5MTHFR and Histamine Intolerance

The causative factors for histamine intolerance are many:

• Genetic susceptibility: MTHFR, DAO, MAO, HNMT, PEMT, etc
• Pathogens
• Nutrient deficiencies: B12, folate, B6, B2, B1, Zn, Cu, C, methionine
• Nutrient excesses: histidine, protein excess in general
• Medications: antibiotics, antacids
• Stress, anxiety, lack of sleep
• Hormonal insufficiciency
• Adrenal fatigue
• Hormonal excess: estrogen dominance, PCOS
• Lifestyle: excessive exercise, alcohol, decreased sleep
• Diet
• Environment: exposures
• Gastrointestinal issues: leaky gut, IBD, IBS

Here is a great article relating histamine intolerance (hives)

http://ajcn.nutrition.org/content/85/5/1185.full.pdf

Dr. Samantha Du Moulin has completed additional training in genetic mutations, including  5MTHFR.